TRPP is a family of transient receptor potential ion channels mutations of which are involved in polycystic kidney disease. Hence the name TRPP is an acronym derived from the phrase Transient Receptor Potential Polycystic. Subcategories TRPP subunits can be divided into two subcategories depending on structural similarity. TRPP1-like The first group, TRPP1-like, contains TRPP1, PKDREJ, PKD1L1, PKD1L2, and PKD1L3. TRPP1 contains numerous N-terminal adhesive domains that are important for cell-cel… (
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