The translocon (commonly known as a translocator or translocation channel) is the complex of proteins associated with the translocation of nascent polypeptides into the interior (cisternal or luminal) space of the endoplasmic reticulum (ER) from the cytosol. This process requires the protein to cross a hydrophobic lipid bilayer. Translocators can also move polypeptides (such as damaged proteins targeted for proteasomes) from the cisternal space of the endoplasmic reticulum to the cytosol. This r… (More on Translocon)