Thioesters are compounds resulting from the bonding of sulfur with an acyl group with the general formula R-S-CO-R'. They are the product of esterification between a carboxylic acid and a thiol (as opposed to an alcohol in regular esters). In biochemistry a thioester connects the acetyl groups in acetyl-CoA and malonyl-CoA. Thioesters and the origin of life Some biochemists believe that the thioester bond was critical for the origin of life. One Nobel Prize winning scientist, Belgium's Christian… (More on Thioesters)