» This article is about the herbicidal product. For information on the herbicidal main active ingredient, see glyphosate. For other uses, see Round Up (disambiguation). Roundup is the brand name of a systemic, broad-spectrum herbicide produced by the U.S. company Monsanto and contains the active ingredient glyphosate. Glyphosate is the most used herbicide in the USA US EPA 2000–2001 Pesticide Market Estimates Agriculture, Home and Garden, and Roundup is the number one selling herbicide w… (More on Roundup)