. Formation and turnover It appears to be the product of the oxidation of unsaturated fatty acids, and may be symptomatic of membrane damage, or damage to mitochondria and lysosomes. Aside from a large lipid content, lipofuscin is known to contain sugars and metals, including mercury, aluminum, iron, copper and zinc.Chris Gaugler, " Lipofuscin", Stanislaus Journal of Biochemical Reviews May 1997 The accumulation of lipofuscin-like material may be the result of an imbalance between formation and… (More on Lipofuscin)