Frosinone is a town and comune in Lazio, central Italy, the capital of the Province of Frosinone Provincia di Frosinone (FR) - Italia: Informazioni. It is located about 75 km south-east of Rome close to the Rome-Naples Autostrada A1. East of Frosinone lies an early gothic Cistercian cloister. Geography Frosinone is located on a hill overlooking the valley of the Sacco River, and is surrounded by the Ernici and Lepini mountain ranges. Traditional home of the Classical clans of Gesuale, Ferrante,… (More on Frosinone)