Dipyridamole (also known commercially by Persantine) is a drug that inhibits thrombus formation when given chronically and causes vasodilation when given at high doses over short time. Mechanism and effects Inhibits Thromboxane synthase, therefore lowering the levels of TXA2 and thus stops the effects of TXA2(platelet aggregation, bronchioconstriction and vasoconstriction. It inhibits the cellular reuptake of adenosine into platelets, red blood cells and endothelial cells leading to increased… (More on Dipyridamole) |