Demeclocycline (marketed as Declomycin, Declostatin and Ledermycin) is a tetracycline antibiotic. It is derived from a strain of Streptomyces aureofaciens. Uses In infections It is officially indicated for the treatment of various types of bacterial infections. Its use as an antibiotic is particularly in Lyme disease, acne and bronchitis. Resistance is gradually becoming more common, and demeclocycline is now rarely used for infections. In SIADH It is widely used (though off-label in many coun… (More on Demeclocycline)