Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1)'s an uncoupling protein found in the mitochondria of brown adipose tissue (BAT). It's used to generate heat by non-shivering thermogenesis. Non-shivering thermogenesis's the primary means of heat generation in hibernating mammals and in human infants. Mechanism The molecular mechanism of UCP1-mediated uncoupling's reasonably well understood; UCP1 provides an alternative pathway by which prot… (
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