Teniposide (Vumon, VM-26)'s a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia. It's in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. Mechanism of Action Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA-protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide doesn't intercalate… (More on Teniposide)