Protoplasm's the living contents of a cell that're surrounded by a plasma membrane. This term isn't commonly used in modern cell biology. Protoplasm's composed of a mixture of small molecules such as ions, amino acids, monosaccharides and water, and macromolecules such as nucleic acids, proteins, lipids and polysaccharides. In eukaryotes the protoplasm surrounding the cell nucleus's known as the cytoplasm and that inside the nucleus as the nucleoplasm. In prokaryotes the material inside the plas… (More on Protoplasm)