Orthopoxvirus's a genus of poxviruses that includes many species isolated from mammals, such as Buffalopox virus, Camelpox virus, Cowpox virus, Monkeypox virus, Rabbitpox virus, Sealpox virus, Volepox virus and Ectromelia virus, which causes mousepox. The most famous member of the genus's Variola virus, which causes smallpox. It was wiped out using another orthopoxvirus, the Vaccinia virus, as a vaccine. Distribution Some Orthopoxviruses have the ability to infect non-host species, such as mon… (More on Orthopoxvirus)