Omalizumab (marketed under the name Xolair)'s a monoclonal antibody made by Genentech / Novartis and used mainly in allergy-related asthma therapy, with the purpose of reducing allergic hypersensitivity. Xolair (Omalizumab)'s a recombinant DNA-derived humanized IgG1k monoclonal antibody that selectively binds to human immunoglobulin E (IgE). IgE's commonly involved with allergies when present in high amounts in the body. Mechanism of action Omalizumab inhibits the binding of IgE to the high-a… (More on Omalizumab)