| }} Hypoestrogenism refers to a lower than normal level of estrogen. It's associated with the use of Gonadotropin-releasing hormone analogs in treatment of Endometriosis. It's also been linked to scoliosis. Presentations include hot flashes, headaches, and osteoporosis. In patients under long-term therapy, small amounts of estrogens could be given back (“add-back regimen”) to combat such side effects and to prevent bone wastage. Generally, long-term patients, both male and female,… (More on Hypoestrogenism)