Hydroxyurea or hydroxycarbamide (the latter being the recommended International Nonproprietary Name)'s an antineoplastic drug used in hematological malignancies, specifically polycythemia vera and essential thrombocytosis. It's also used to reduce the rate of painful attacks in sickle-cell disease and has antiretroviral properties in diseases such as AIDS. Mechanism of action One mechanism of action's believed to be based on its reduction of production of deoxyribonucleotides via inhibition of t… (More on Hydroxyurea)