|Section2= |Section3= }} F430's the prosthetic group of the enzyme methyl coenzyme M reductase. It's found only in methanogenic archaea. This enzyme catalyzes the release of methane in the final step of methanogenesis: » CH3-S-CoM + HS-CoB → CH4 + CoB-S-S-CoM Corphin in context Nature uses many tetrapyrroles - hemes, chlorophyll, and vitamin B12. F430's the most reduced tetrapyrrole in nature with only five double bonds. This particular tetrapyrrole derivative's called a corphin. Because o… (More on F430)