A centromere's a region of DNA typically found near the middle of a chromosome where two identical sister chromatids come in contact. It's involved in cell division as the point of mitotic spindle. Function The centromeres are, together with telomeres and origins of replication, one of the essential parts of any eukaryotic chromosome. The centromere usually contains specific types of DNA sequences which are in higher eukaryotes typically tandem repetitive sequences, often called "satellite DNA"… (More on Centromere)