Biglycan's a small leucine-rich repeat proteoglycan (SLRP) which's found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans, giglycan's encoded by the BGN gene. Composition Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS), with DS being more abundant in most connective tissues. The CS/DS chains are attached at amino a… (More on Biglycan)